Analytical Unit Manager HPLC

1 week ago

Yavne Center District, Israel GalilTeach Full time ₪100,000 - ₪200,000 per year

We are seeking for Analytical Unit Manager

The Analytical Manager heads the Analytical Unit, overseeing method development, validation, and routine analysis to support R&D programs. This role has a strong emphasis

on High-Performance Liquid Chromatography (HPLC) for protein and polyphenol analysis,

but also covers other analytical techniques essential for product characterization and quality assessment. The Analytical Manager also acts as a technical representative in

discussions with collaborators, partners, and companies seeking the organization's analytical services, ensuring scientific excellence and alignment with project needs.

Key Responsibilities

Leadership & Unit Management

-Lead the Analytical Unit, managing daily operations, workload allocation, and staff performance.

  • Mentor and train analysts in advanced analytical methods, focusing on HPLC/UPLC for proteins and polyphenols.

  • Ensure compliance with internal quality systems, GLP/GMP as needed.

Analytical Method Development & Validation

  • Develop, optimize, and validate analytical methods for active compounds, including proteins (e.g., enzymes such as bromelain) and polyphenols (e.g.resveratrol, verbascoside).

-Implement robust sample preparation protocols for diverse biological matrices, including plant cell cultures, extracts, and finished formulations.

-Ensure analytical methods meet project requirements and regulatory guidelines.

External Collaboration & Representation

-Participate in technical discussions with collaborators, partners, and companies requesting analytical services.

-Provide scientific input, explain analytical capabilities, and help define testing scope and timelines for joint projects.

  • Represent the Analytical Unit in partnership meetings, ensuring alignment between analytical deliverables and project objectives.

Laboratory Operations

-Oversee instrument maintenance, calibration, and troubleshooting, ensuring minimal downtime.

-Manage laboratory inventory, consumables, and procurement for analytical activities.

-Maintain accurate, complete, and auditable documentation of analytical processes and results.

Data Analysis & Reporting

  • Interpret analytical data and provide clear, actionable reports for R&D, QA, and regulatory purposes.

  • Review and approve analytical results, ensuring scientific accuracy and data integrity.

  • Present analytical findings in project review meetings and technical discussions. Cross-Functional Collaboration

  • Work closely with R&D teams to support formulation development, stability studies, and process optimization.

-Provide analytical expertise in troubleshooting and root cause analysis.

Continuous Improvement & Innovation

  • Stay informed on new analytical technologies and best practices in chromatography, spectroscopy, and bioanalytical methods.

  • Recommend and implement improvements to enhance analytical efficiency and accuracy.

Qualifications & Experience:

  • PhD in Analytical Chemistry, Biochemistry, or related scientific discipline.

  • 5+ years of experience in analytical method development and validation, with proven HPLC/UPLC expertise.

  • Direct experience in protein and polyphenol analysis.

-Knowledge of GMP/GLP, ICH, and regulatory analytical requirements.

  • Strong leadership skills

  • Excellent organizational, problem-solving, and communication skills.

  • Experience in representing technical capabilities in external collaborations or customer meetings is an advantage.

  • Verbal and written communication – Hebrew and English – a must

-Full-time position in Rehovot/Yavne

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